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Table 2 Antimicrobial activity (MIC = μM/ml) of newly synthesized compounds

From: Synthesis, SAR and in vitro therapeutic potentials of thiazolidine-2,4-diones

Compound Minimum inhibitory concentration (μΜ/ml)
Bacteria Fungi
B. subtilis S. aureus K. pneumonia E. coli S. typhi A. niger C. albicans
1 9.90 4.90 9.90 4.90 4.90 4.90 4.90
2 10.40 5.21 5.21 5.21 20.80 5.21 5.21
3 4.50 4.50 9.12 9.12 4.50 4.50 4.50
4 9.90 4.99 9.90 4.50 4.99 4.99 4.99
5 5.65 5.65 11.30 11.30 5.65 5.65 5.65
6 5.00 5.00 10.06 4.99 5.00 10.06 20.10
7 9.90 4.99 4.99 4.99 4.99 9.90 4.99
8 4.50 4.50 4.50 5.00 4.50 4.50 4.50
9 8.79 4.30 8.79 8.79 4.30 4.30 4.30
10 4.20 4.20 4.20 8.40 4.20 4.20 4.20
11 9.40 4.70 4.70 4.70 4.70 4.70 4.70
12 10.60 10.60 10.60 5.31 5.31 5.31 5.31
13 10.40 5.21 10.40 5.21 5.21 2.60 5.21
14 5.21 5.21 10.60 10.40 5.21 2.60 5.21
15 5.31 5.31 2.60 5.31 5.31 5.31 5.31
16 5.31 5.31 10.60 5.31 5.31 5.31 5.31
17 11.30 5.65 11.30 5.65 5.65 5.65 5.65
18 4.90 4.90 9.90 4.90 4.90 4.90 4.90
19 4.70 4.70 9.40 4.70 4.70 4.70 4.70
20 5.40 5.40 10.80 5.40 5.40 5.40 5.40
21 5.30 5.30 10.70 5.30 5.30 5.30 5.30
Cefadroxil 3.40 1.71 3.40 1.71 1.71
Fluconazole 4.08 4.08
  1. Compound numbers and their significant values are given in italic