Table 1 Results of the in vitro antibacterial activity (MIC values µg/ml) of the synthesized compounds 1, 2, 4, 5, 7a, 7b, 8a, 8b, 10a, 10b, 11a and 11b vis-a-vis bacteria tested (Escherichia coli ATCC, Pseudomonas aeruginosa ATCC, Staphylococcus aureus ATCC, Acinetobacter ATCC, Escherichia coli BLSE, Acinetobacter BLSE, Staphylococcus aureus MLSB and Klebsiella pneumonia BLSE)
E. coli ATCC | PA ATCC | SA ATCC | Acin ATCC | E. coli ESBL | Acin ESBL | SA MLSB | KP ESBL | |
|---|---|---|---|---|---|---|---|---|
1 | – | – | – | 62.5 | 250 | 31.25 | 250 | 250 |
2 | 250 | 125 | 125 | – | – | 250 | – | – |
4 | 125 | – | 250 | – | – | 250 | – | – |
5 | 125 | 250 | 250 | – | – | 250 | – | – |
7a | – | – | – | 250 | 125 | 62.5 | – | 62.5 |
7b | 125 | – | – | 125 | 62.5 | 62.5 | – | 62.5 |
8a | 62.5 | 62.5 | – | 125 | 125 | 62.5 | – | 125 |
8b | – | – | – | – | – | – | 125 | – |
10a | 125 | 125 | – | 125 | – | 62.5 | – | – |
10b | – | – | – | – | – | – | – | – |
11a | – | 125 | – | 125 | 62.5 | 125 | – | 62.5 |
11b | – | – | – | 250 | 62.5 | 125 | – | 62.5 |
DMSO | – | – | – | – | – | – | – | – |
Chlor | 4 | 7.5 | 2.5 | – | 5 | – | 3 | – |