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Table 3 Multicomponent synthesis of isoxazole derivatives

From: Green multicomponent synthesis, antimicrobial and antioxidant evaluation of novel 5-amino-isoxazole-4-carbonitriles

Entry Conditions Catalyst Time (min) Yield (%) References
1 EtOH, reflux DABCOa 1.5–15 65–85 [13]
2 CH3CN, rt 3600–9000 70–93 [14]
3 aq. EtOH, hν CH3CO2Na 5–10 61–89 [15]
4 H2O, rt KPb 30–150 85–96 [16]
5 H2O, rt Boric acid 50–1440 82–95 [17]
  1. a1,4-Diazabicyclo[2]octane
  2. bPotassium phthalimide