Skip to main content

Advertisement

Table 4 In silico bioavailability prediction and cLogP value

From: Design, synthesis, ADME prediction and pharmacological evaluation of novel benzimidazole-1,2,3-triazole-sulfonamide hybrids as antimicrobial and antiproliferative agents

Compd. no In silico Bioavailability and cLogP Bioavailability score
cLogP Lipinski Ghose Veber
4a 3.19 Yes No No 0.55
4b 2.31 Yes Yes No 0.55
4c 3.24 Yes Yes No 0.55
4d 3.19 Yes Yes No 0.55
4e 3.34 Yes No; 1 violation No 0.55
4f 1.52 Yes Yes No 0.55
6a 4.11 No No No 0.17
6b 2.35 No No No 0.17
6c 4.20 No No No 0.17
6d 4.10 No No No 0.17
6e 4.41 No No No 0.17
6f 0.75 No No No 0.17
Cipro. − 0.70 Yes Yes Yes 0.55
Fluco. − 0.12 Yes Yes Yes 0.55