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Table 2 In vitro antiproliferative activities (IC50 represented as μM ± SD) of the newly synthesized compounds against three human cancer cell lines

From: Design, synthesis, ADME prediction and pharmacological evaluation of novel benzimidazole-1,2,3-triazole-sulfonamide hybrids as antimicrobial and antiproliferative agents

Compd. no IC50 PC-3 IC50 HepG2 IC50 HEK293
4a 66 66 70
4b 61 62 65
4c 80 77 81
4d 90 91 92
4e 85 86 83
4f 104 106 103
6a 61 61 64
6b 55 56 59
6c 73 70 74
6d 82 83 84
6e 77 79 75
6f 95 97 95
  1. IC50 values are presented as mean values of three independent experiments. SD were < 10%