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Table 1 Antimicrobial screening results of compounds 4a–f and 6a–f presented as MIC (μg/mL)

From: Design, synthesis, ADME prediction and pharmacological evaluation of novel benzimidazole-1,2,3-triazole-sulfonamide hybrids as antimicrobial and antiproliferative agents

Compd. no

Gram-positive organisms

Gram-negative organisms

Fungi organisms

Bc

Sa

Pa

Ec

Ab

Ca

4a

64

64

256

128

128

128

4b

128

128

128

128

256

256

4c

256

128

256

64

256

256

4d

256

128

256

64

256

256

4e

256

128

256

64

256

256

4f

512

512

256

256

512

512

6a

32

32

64

64

64

32

6b

64

64

64

64

128

128

6c

128

64

128

32

256

256

6d

128

64

128

32

256

256

6e

128

64

128

32

256

256

6f

256

256

128

128

256

256

Ciprofloxacin

8

4

8

4

–

–

Fluconazole

–

–

–

–

8

4