Table 6 Cytotoxicity (IC50 = µM) of triarylethylene analogs (20–22)
From: Estrogen alpha receptor antagonists for the treatment of breast cancer: a review
Compound No. | Cancer cell lines | |
|---|---|---|
MDA-MB-231 | MCF-7 | |
20 | 11.4 ± 4.2 | 16.9 ± 7.7 |
21 | 16.9 ± 7.7 | > 50 |
22 | 12.2 ± 5.3 | > 50 |
Tamoxifen | > 50 | 50 |
Ospemifene | > 50 | > 50 |