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Table 4 In vitro anticancer results of 13–14

From: Estrogen alpha receptor antagonists for the treatment of breast cancer: a review

Compound No. Tumor cell lines (IC50 = µM)
MCF-7 Ishikawa
13 4.52 ± 2.47 11.58 ± 3.81
14 7.31 ± 2.12 8.43 ± 1.06
Tamoxifen 11.35 ± 3.13 16.47 ± 2.04