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Table 3 In vitro antiproliferative activity (IC
50 =
µg/ml) of compound 12
From:
Estrogen alpha receptor antagonists for the treatment of breast cancer: a review
Compound No.
Cancer cell lines
MCF-7
MDA-MB-435
12
LC
50
TGI
GI
50
LC
50
TGI
GI
50
74.5
40
< 10
> 80
78.2
75.3
Tamoxifen
29.5
11.2
< 10
54.2
21.5
< 10
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