Table 3 In vitro antiproliferative activity (IC50 = µg/ml) of compound 12
From: Estrogen alpha receptor antagonists for the treatment of breast cancer: a review
Compound No. | Cancer cell lines | |||||
|---|---|---|---|---|---|---|
MCF-7 | MDA-MB-435 | |||||
12 | LC50 | TGI | GI50 | LC50 | TGI | GI50 |
74.5 | 40 | < 10 | > 80 | 78.2 | 75.3 | |
Tamoxifen | 29.5 | 11.2 | < 10 | 54.2 | 21.5 | < 10 |