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Table 3 In vitro antiproliferative activity (IC50 = µg/ml) of compound 12

From: Estrogen alpha receptor antagonists for the treatment of breast cancer: a review

Compound No. Cancer cell lines
MCF-7 MDA-MB-435
12 LC50 TGI GI50 LC50 TGI GI50
74.5 40 < 10 > 80 78.2 75.3
Tamoxifen 29.5 11.2 < 10 54.2 21.5 < 10
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BMC Chemistry

ISSN: 2661-801X

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