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Table 16 In vitro antiproliferative activity of tetrahydroisoquinoline derivatives 48–50
From:
Estrogen alpha receptor antagonists for the treatment of breast cancer: a review
Compound No.
Tumor cell lines (IC
50
= µg/ml)
Ishikawa
MCF-7
MDA-MB-231
48
0.08
0.2
0.13
49
0.09
0.61
1.36
50
0.11
0.25
0.23
Tamoxifen
7.87
3.99
7.85
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