Table 14 Cytotoxicity of genistein derivatives 43–45
From: Estrogen alpha receptor antagonists for the treatment of breast cancer: a review
| Compound No. | Cancer cell lines (IC50 = μM) | ||
|---|---|---|---|
| MCF-7 | T47D | 21PT | |
| 43 | 1.0 | 1.1 | 2.6 |
| 44 | 0.8 | 0.9 | 0.9 |
| 45 | 1.2 | 1.2 | 0.9 |
| Genistein | 14 | 15 | 16.4 |