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Table 14 Cytotoxicity of genistein derivatives 43–45

From: Estrogen alpha receptor antagonists for the treatment of breast cancer: a review

Compound No. Cancer cell lines (IC50 = μM)
MCF-7 T47D 21PT
43 1.0 1.1 2.6
44 0.8 0.9 0.9
45 1.2 1.2 0.9
Genistein 14 15 16.4