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Table 4 Anticancer activity results of synthesized compounds

From: Design, synthesis and biological potential of heterocyclic benzoxazole scaffolds as promising antimicrobial and anticancer agents

Anticancer screening results (IC50 = µM)
Compound no. Cancer cell line (HCT 116) Compound no. Cancer cell line (HCT 116)
1 97.5 11 130.4
2 73.1 12 > 225.1
3 108.7 13 > 230.3
4 22.5 14 90.0
5 85.3 15 40.7
6 84.6 16 38.3
7 72.0 17 177.9
8 > 254.2 18 148.7
9 66.1 19 50.0
10 175.1 20 200.1
5-Fluorouracil 12.2 5-Fluorouracil 12.2