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Table 1 The physicochemical properties of synthesized benzoxazole derivatives (126)

From: Benzoxazole derivatives: design, synthesis and biological evaluation

Comp. Molecular formula Molecular structure M. Wt. M. Pt. Rf valuea % yield
1. C24H19N5O2S 441.50 180–182 0.58 95
2. C25H21N5O3S 471.53 242–244 0.52 93
3. C25H21N5O3S 471.53 224–225 0.51 86
4. C26H23N5O4S 501.56 233–235 0.55 85
5. C26H23N5O4S 501.56 256–258 0.55 82
6. C27H25N5O5S 531.58 263–265 0.56 85
7. C27H25N5O2S 483.58 184–186 0.60 87
8. C25H18F3N5O2S 509.50 190–192 0.53 88
9. C25H18N6O2S 466.51 278–280 0.51 91
10. C31H25N5O3S 547.63 261–263 0.55 85
11. C24H18N6O4S 486.50 283–285 0.48 92
12. C24H18N6O4S 486.50 243–245 0.47 91
13. C24H18N6O4S 486.50 259–261 0.45 95
14. C24H18ClN5O2S 475.95 200–202 0.49 92
15. C24H18ClN5O2S 475.95 237–239 0.44 92
16. C24H17Cl2N5O2S 510.39 257–259 0.46 94
17. C24H16F3N5O2S 495.47 178–180 0.52 83
18. C24H18FN5O2S 459.49 184–186 0.53 93
19. C24H18BrN5O2S 520.40 247–249 0.51 89
20. C24H18BrN5O2S 520.40 207–209 0.52 83
21. C26H20N6O2S 480.54 283–285 0.45 91
22. C26H21N5O2S 467.54 187–189 0.48 92
23. C23H18N6O2S 442.49 186–188 0.42 90
24. C22H17N5O2S2 447.53 205–207 0.49 91
25. C23H19N5O2S2 461.55 218–220 0.52 93
26. C24H19N5O3S 457.50 192–194 0.45 95
  1. aTLC mobile phase: chloroform: methanol (9:1)