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Table 2 EC50 values of some title compounds against Rs, Cc and Fg

From: Design and synthesis of novel 3-(thiophen-2-yl)-1,5-dihydro-2H-pyrrol-2-one derivatives bearing a hydrazone moiety as potential fungicides

Compd. Tested fungus Regression equation R EC50 (µg/mL)
5b Rs y = 0.76x + 4.73 0.99 2.28 ± 3.00
Cc y = 0.81x + 4.28 0.95 7.65 ± 5.31
5d Rs y = 1.42x + 3.57 0.98 5.23 ± 3.74
Cc y = 1.60x + 2.95 0.98 9.97 ± 8.90
5e Rs y = 0.87x + 4.91 0.99 1.26 ± 1.12
Cc y = 1.42x + 3.89 0.99 6.04 ± 5.35
Fg y = 2.32x + 3.17 0.97 6.13 ± 4.49
5f Rs y = 0.50x + 4.74 0.99 3.32 ± 2.74
Cc y = 1.25x + 3.97 0.99 6.66 ± 5.33
Fg y = 1.74x + 3.54 0.99 6.90 ± 4.96
5g Rs y = 0.38x + 4.77 0.96 4.13 ± 2.83
Cc y = 1.32x + 3.82 0.99 7.84 ± 7.03
Fg y = 1.25x + 3.87 0.96 8.03 ± 5.01
5n Rs y = 1.26x + 4.31 0.99 3.56 ± 3.16
Cc y = 1.35x + 3.81 0.97 7.59 ± 5.12
5o Rs y = 1.42x + 3.79 0.98 7.15 ± 5.62
Cc y = 1.47x + 3.56 0.99 9.47 ± 8.02
Fg y = 1.97x + 3.10 0.99 7.22 ± 6.01
5p Rs y = 2.41x + 3.49 0.99 2.22 ± 1.68
Cc y = 4.22x + 1.87 0.99 5.52 ± 5.49
Fg y = 3.56x + 2.04 0.98 6.77 ± 5.14
5q Rs y = 1.76x + 3.73 0.99 5.29 ± 4.54
Cc y = 1.68x + 3.29 0.99 6.41 ± 4.96
Fg y = 3.79x + 1.30 0.99 7.63 ± 5.81
5r Rs y = 1.13x + 3.70 0.98 9.89 ± 7.18
Fg y = 1.33x + 3.47 0.99 8.85 ± 8.26
5t Rs y = 1.27x + 3.81 0.99 8.62 ± 7.06
Cc y = 1.39x + 3.24 0.98 7.53 ± 6.89
Fg y = 1.37x + 3.85 0.97 6.02 ± 5.26
Drazoxolon a Rs y = 2.54x + 4.37 0.99 1.77 ± 1.62
Cc y = 0.82x + 3.94 0.99 19.46 ± 3.93
Fg y = 2.04x + 3.88 0.99 3.53 ± 2.72
  1. Average of three replicates
  2. a A commercial agricultural fungicide drazoxolon was used for comparison of antifungal activity