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Table 3 Contributions of individual flavonoids to the overall enzyme inhibitory effect

From: Inhibitory effects against α-glucosidase and α-amylase of the flavonoids-rich extract from Scutellaria baicalensis shoots and interpretation of structure–activity relationship of its eight flavonoids by a refined assign-score method

Flavonoids

Content in extract (mg/g)a

Inhibitory effects (μg acarbose/μg)

Contribution (%)

α-glucosidase

α-amylase

α-glucosidase

α-amylase

Baicalein

153.543

3.58 ± 0.07

2.07 ± 0.02

23.29 ± 1.03

23.37 ± 0.98

Scutellarin

109.421

3.18 ± 0.06

1.84 ± 0.02

14.74 ± 0.27

14.80 ± 0.66

Apigenin

45.609

4.31 ± 0.08

2.36 ± 0.03

8.32 ± 0.56

7.91 ± 0.87

Chrysin

62.222

2.36 ± 0.03

1.51 ± 0.02

6.20 ± 0.08

6.91 ± 0.21

Baicalin

65.331

1.68 ± 0.02

1.03 ± 0.01

4.65 ± 0.12

4.95 ± 0.13

Apigenin-7-O-G

35.783

1.83 ± 0.02

1.04 ± 0.01

2.77 ± 0.05

2.74 ± 0.09

Chrysin-7-O-G

51.976

1.63 ± 0.01

0.69 ± 0.01

1.01 ± 0.03

2.63 ± 0.07

Isocarthamidin-7-O-G

50.007

0.46 ± 0.01

0.23 ± 0.01

0.97 ± 0.11

0.85 ± 0.01

Total of the eight

573.886

19.03 ± 0.30

10.77 ± 0.13

61.95 ± 2.25

64.16 ± 3.02

The extract

1000

2.36 ± 0.05

1.36 ± 0.02

100

100

  1. Data are the mean ± SD of three repeated tests
  2. G: glucuronide
  3. a The content of each flavonoid was cited from supplementary material of Li et al. [20]