Skip to main content

Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Table 2 Assigned scores for the eight high content flavonoids in flavonoids-rich extract from S. baicalensis shoots

From: Inhibitory effects against α-glucosidase and α-amylase of the flavonoids-rich extract from Scutellaria baicalensis shoots and interpretation of structure–activity relationship of its eight flavonoids by a refined assign-score method

Flavonoids Number of structural features Total score of structural features
Double bond (10 scores) C7-OH (4 scores) C4′-OH (4 scores) C6-OH (3 scores) Sugar moiety (− 1 score)
Apigenin (1)a 7 1 1 0 0 78
Baicalein (2) 7 1 0 1 0 77
Scutellarin (3) 7 0 1 1 1 76
Chrysin (4) 7 1 0 0 0 74
Apigenin-7-O-G (5) 7 0 1 0 1 73
Baicalin (6) 7 0 0 1 1 72
Chrysin-7-O-G (7) 7 0 0 0 1 69
Isocarthamidin-7-O-G (8) 6 0 1 1 1 66
  1. G glucuronide
  2. aEight flavonoids are arranged in a decreasing order of inhibitory effects against both α-glucosidase and α-amylase