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Table 1 IC50 values for enzyme inhibitory effects of the flavonoids-rich extract, eight flavonoids and acarbose

From: Inhibitory effects against α-glucosidase and α-amylase of the flavonoids-rich extract from Scutellaria baicalensis shoots and interpretation of structure–activity relationship of its eight flavonoids by a refined assign-score method

Flavonoids

IC50 (μg/mL)a

α-Glucosidase

α-Amylase

Acarbose

996.02 ± 21.34

678.43 ± 16.52

Extract

421.54 ± 10.01

498.59 ± 11.87

Apigenin

231.13 ± 5.35

287.53 ± 5.39

Baicalein

277.94 ± 6.21

336.22 ± 6.31

Scutellarin

313.25 ± 7.28

369.52 ± 8.43

Chrysin

422.67 ± 9.37

450.16 ± 10.45

Apigenin-7-O-G

543.28 ± 11.41

653.98 ± 15.28

Baicalin

591.58 ± 12.21

658.67 ± 16.38

Chrysin-7-O-G

612.13 ± 15.34

980.73 ± 18.34

Isocarthamidin-7-O-G

2149.78 ± 54.25

2941.25 ± 62.12

  1. G glucuronide
  2. aData are the mean ± SD of three repeated tests