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Table 1 IC50 values for enzyme inhibitory effects of the flavonoids-rich extract, eight flavonoids and acarbose

From: Inhibitory effects against α-glucosidase and α-amylase of the flavonoids-rich extract from Scutellaria baicalensis shoots and interpretation of structure–activity relationship of its eight flavonoids by a refined assign-score method

Flavonoids IC50 (μg/mL)a
α-Glucosidase α-Amylase
Acarbose 996.02 ± 21.34 678.43 ± 16.52
Extract 421.54 ± 10.01 498.59 ± 11.87
Apigenin 231.13 ± 5.35 287.53 ± 5.39
Baicalein 277.94 ± 6.21 336.22 ± 6.31
Scutellarin 313.25 ± 7.28 369.52 ± 8.43
Chrysin 422.67 ± 9.37 450.16 ± 10.45
Apigenin-7-O-G 543.28 ± 11.41 653.98 ± 15.28
Baicalin 591.58 ± 12.21 658.67 ± 16.38
Chrysin-7-O-G 612.13 ± 15.34 980.73 ± 18.34
Isocarthamidin-7-O-G 2149.78 ± 54.25 2941.25 ± 62.12
  1. G glucuronide
  2. aData are the mean ± SD of three repeated tests