From: Crystal structure, DFT calculations and evaluation of 2-(2-(3,4-dimethoxyphenyl)ethyl)isoindoline-1,3-dione as AChE inhibitor
Inhibitors
Compound
LD50 (mice)
1
> 1600 mg/kg
Donepezil
30 mg/kg [41]
Physostigmine
3 mg/kg [42]
Neostigmine
0.54 ± 0.03 mg/kg [1]
Pyridostigmine
37.5 mg/kg [41]