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Table 1 Covalent and non-covalent DprE1inhibitors

From: Decaprenyl-phosphoryl-ribose 2′-epimerase (DprE1): challenging target for antitubercular drug discovery

Covalent inhibitors Non covalent inhibitors
Compound Structure References Compound Structure References
BTZ043 [23] 1–4 Azaindoles [34]
DNB1 [35] 2-Carboxyquinoxalines [32]
377790 [26] 4-AQs [36]
cBT [16] 8-Pyrrole-BTZ [37]
BTO [38] 1,3-BTZ azide [39]
VI-9376 [40] Pyrazolopyridones [33]
PBTZ [17] 1,2,4-Triazole containing 1,4-BTZ derivatives [41]