Table 3 Anticancer activity results of the synthesized bis-pyrimidine molecules
Anticancer activity (IC50 = µmol/mL) | |||
|---|---|---|---|
Compound no. | Cancer cell line (HCT-116) | Compound no. | Cancer cell line (HCT-116) |
s1. | 12.56 | s10. | 5.08 |
s2. | 5.16 | s11. | 2.96 |
s3. | 1.16 | s12. | 4.44 |
s4. | 13.16 | s13. | 4.27 |
s5. | 11.79 | s14. | 3.77 |
s6. | 12.22 | s15. | 2.63 |
s7. | 6.72 | s16. | 2.18 |
s8. | 4.91 | s17. | 2.64 |
s9. | 3.81 | s18. | 3.59 |
5-Fluorouracil | 0.83 | 5-Fluorouracil | 0.83 |