Skip to main content

Advertisement

Table 3 Anticancer activity results of the synthesized bis-pyrimidine molecules

From: Design, synthesis, antimicrobial and cytotoxicity study on human colorectal carcinoma cell line of new 4,4′-(1,4-phenylene)bis(pyrimidin-2-amine) derivatives

Anticancer activity (IC50 = µmol/mL)
Compound no. Cancer cell line (HCT-116) Compound no. Cancer cell line (HCT-116)
s1. 12.56 s10. 5.08
s2. 5.16 s11. 2.96
s3. 1.16 s12. 4.44
s4. 13.16 s13. 4.27
s5. 11.79 s14. 3.77
s6. 12.22 s15. 2.63
s7. 6.72 s16. 2.18
s8. 4.91 s17. 2.64
s9. 3.81 s18. 3.59
5-Fluorouracil 0.83 5-Fluorouracil 0.83
  1. HCT-116 human colorectal carcinoma