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Table 1 Cytotoxicity (IC50, μmol mL−1) of the synthesized compounds (3a11b) against MCF-7 and HCT-116 human cancer cell lines

From: A facile synthesis, and antimicrobial and anticancer activities of some pyridines, thioamides, thiazole, urea, quinazoline, β-naphthyl carbamate, and pyrano[2,3-d]thiazole derivatives

Compound no. MCF-7 HCT-116 Compound no. MCF-7 HCT-116
IC50 (µmol mL−1) IC50 (µmol mL−1) IC50 (µmol mL−1) IC50 (µmol mL−1)
3a 23.6 346 7 14.2 > 500
4a 13.5 291 8 23.5 > 500
4d 15.1 242 9 60.2 316
4e 222 193 11a 203 215
4f 238 124 11b 404 180
5 9.65 213    
Imatinib 24.5 Imatinib 24.5
Cisplatin   2.43 Cisplatin   2.43