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Table 3 Application of standard addition technique to the analysis of PAR, PSE and CET in Allercet Cold® capsules using the proposed spectrophotometric methods

From: Analysis of paracetamol, pseudoephedrine and cetirizine in Allercet Cold® capsules using spectrophotometric techniques

Drug RSDM method SDR method DRZC method PCCA method
Claimed amount taken Added Recovery %a, b Claimed amount taken Added Recovery %a, b Claimed amount taken Added Recovery %a, b Claimed amount taken Added Recovery %a, b
PAR 10.00 (µg mL−1) 5.000 104.6 10.00 (µg mL−1)  5.000 105.9 10.00 (µg mL−1) 5.000 101.1 10.00 (µg mL−1) 5.000 103.1
10.00 104.0 10.00 104.9 10.00 100.8 10.00 103.8
15.00 105.1 15.00 105.3 15.00 101.2 15.00 102.3
Mean ± SD 104.6 ± 0.5210 Mean ± SD 105.4 ± 0.5490 Mean ± SD 101.0 ± 0.2330 Mean ± SD 103.1 ± 0.7360
PSE 100.75 (µg mL−1)* 50.00 104.0 100.8 (µg mL−1) 50.00 105.6 100.8 (µg mL−1) 50.00 104.1 100.8 (µg mL−1) 50.00 102.9
100.0 103.2 100.0 104.3 100.0 105.0 100.0 102.8
200.0 103.2 200.0 105.0 200.0 104.9 200.0 102.4
Mean ± SD 103.5 ± 0.4780 Mean ± SD 105.0 ± 0.6500 Mean ± SD 104.6 ± 0.5030 Mean ± SD 102.7 ± 0.2310
CET 2.250 (µg mL−1)* 2.000 105.7 2.250 (µg mL−1) 2.000 105.9 2.250 (µg mL−1) 2.000 103.8 2.250 (µg mL−1) 2.000 101.9
2.500 104.5 2.500 104.5 2.500 102.9 2.500 101.0
10.00 105.6 10.00 104.0 10.00 102.8 10.00 101.1
Mean ± SD 105.3 ± 0.6970 Mean ± SD 104.8 ± 1.018 Mean ± SD 103.2 ± 0.5460 Mean ± SD 101.3 ± 0.4800
  1. * Amount spiked was 100.00 µg mL−1 for PSE and 2.00 µg mL−1 for CET
  2. aAverage of three experiments
  3. b Recovery of the claimed amount taken