From: Enhancement of oral bioavailability of doxorubicin through surface modified biodegradable polymeric nanoparticles
Parameters
Cmax (ng/ml)
Tmax (h)
t1/2
AUC0−t (ng h/ml)
AUC0−∞ (ng h/ml)
Keli (h−1)
Rel Bio
DOX-S
206.2
2.00
17.08
2130.75
3232.49
0.04
PEGylated-DOX-PLGA-NPs
1398.19***
36.64
20577.90***
44664.33***
0.02
9.7