BMC Chemistry

Table 1 Antimicrobial (MIC = µM/ml) and anticancer (IC₅₀ = µM/ml) screening results of 2-(1-benzoyl-1H-benzo[d]imidazole-2-ylthio)-2-ylthio)-N-substituted acetamides

From: Synthesis and evaluation of antimicrobial, antitubercular and anticancer activities of 2-(1-benzoyl-1H-benzo[d]imidazol-2-ylthio)-N-substituted acetamides

Comp. no.	Microbial strains							Cancer cell lines
Comp. no.	S. aureus	B. cereus	B. subtilis	S. typhi	E. coli	C. albicans	A. niger	MCF7	HCT116
1	0.032	0.032	0.032	0.032	0.032	0.032	0.032	0.0774	> 0.2581
2	0.031	0.031	0.031	0.031	0.031	0.015	0.031	0.0047	0.0839
3	0.031	0.031	0.031	0.031	0.031	0.015	0.031	0.0247	0.1973
4	0.030	0.030	0.030	0.030	0.030	0.015	0.030	0.0356	0.0594
5	0.030	0.030	0.030	0.030	0.030	0.015	0.030	0.0831	0.1307
6	0.027	0.027	0.027	0.027	0.027	0.014	0.027	0.0898	0.0833
7	0.027	0.027	0.027	0.027	0.027	0.027	0.027	0.0558	0.0965
8	0.027	0.027	0.027	0.027	0.027	0.013	0.027	0.0686	0.1072
9	0.027	0.027	0.027	0.027	0.027	0.013	0.027	> 0.2144	0.0643
10	0.029	0.029	0.029	0.029	0.029	0.015	0.029	0.0786	0.0058
11	0.027	0.027	0.027	0.027	0.027	0.013	0.027	0.1606	0.0236
12	0.031	0.031	0.031	0.031	0.031	0.016	0.031	0.1245	0.0398
13	0.030	0.030	0.030	0.030	0.030	0.015	0.030	0.1348	0.0963
14	0.030	0.030	0.030	0.030	0.030	0.030	0.030	0.0958	0.0958
15	0.030	0.030	0.030	0.059	0.030	0.030	0.030	0.0950	0.0594
16	0.031	0.031	0.031	0.031	0.031	0.016	0.031	0.1245	0.0872
17	0.030	0.030	0.030	0.030	0.030	0.015	0.030	–	–
18	0.030	0.030	0.030	0.030	0.030	0.015	0.030	–	–
19	0.031	0.031	0.031	0.031	0.031	0.016	0.031	–	–
20	0.030	0.030	0.030	0.030	0.030	0.015	0.030	–	–
Cefadroxil	0.37	0.37	0.37	0.37	0.37	–	–	–	–
Fluconazole	–		–		–	0.47	0.47	–	–
5-FU	–	–	–	–	–	–	–	–	0.0125
Tamoxifen	–	–	–	–	–	–	–	0.0043	–

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