Table 4 Summary of the statistics quantitative property–larvicidal activity relationship models for activity against fourth instar of Cx. quinquefasciatus
Statistical parameter | IV instar | |||||
|---|---|---|---|---|---|---|
Model 1 | Model 2 | Model 3 | Model 4 | Model 5 | Model 6 | |
n | 50 | 50 | 47 | 47 | 39 | 39 |
Q2 | 0.759 | 0.630 | 0.761 | 0.751 | 0.840 | 0.818 |
R2 | 0.829 | 0.812 | 0.880 | 0.880 | 0.929 | 0.917 |
F | 20.9 | 20.2 | 24.1 | 23.8 | 34.3 | 29.6 |
s | 0.293 | 0.297 | 0.022 | 0.021 | 0.151 | 0.162 |
Descriptors | Contributions | |||||
|---|---|---|---|---|---|---|
Model 1 | Model 2 | Model 3 | Model 4 | Model 5 | Model 6 | |
J | − 2.3271 | − 1.6812 | WC | WC | − 0.0638 | WC |
MlogP | 0.3632 | 0.3222 | WC | WC | 1.5415 | 1.1347 |
TIE | 0.0843 | 0.0929 | 0.16824 | 0.1684 | 0.2377 | 0.0467 |
AMR | 0.0441 | WC | WC | WC | WC | WC |
Qtot | WC | WC | 0.4735 | 0.5324 | WC | WC |
BAC | WC | − 0.0535 | WC | WC | WC | WC |
Hy | WC | WC | − 0.7359 | − 0.4735 | WC | WC |
Æž | WC | WC | 0.3068 | WC | WC | WC |
m | WC | WC | WC | 0.0927 | 0.5698 | 0.6654 |
E HOMO | WC | WC | WC | WC | 0.2377 | 0.2486 |
Intercept | − 0.3266 | − 0.3421 | − 2.3992 | − 2.3891 | 7.8613 | 4.817 |