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Table 2 Summary of the statistics quantitative structure–larvicidal activity relationship models for activity against fourth instar of Cx. quinquefasciatus

From: In vitro and in silico studies of terpenes, terpenoids and related compounds with larvicidal and pupaecidal activity against Culex quinquefasciatus Say (Diptera: Culicidae)

Statistical parameter

IV instar

Model 1

Model 2

Model 3

Model 4

Model 5

Model 6

n

50

50

47

47

39

39

Q2

0.793

0.75.34

0.781

0.759

0.851

0.832

R2

0.828

0.78.73

0.881

0.858

0.965

0.957

F

14.5

11.1

21.8

21.3

49.2

39.4

s

0.291

0.301

0.231

0.234

0.137

0.152

Descriptors

Contributions

Model 1

Model 2

Model 3

Model 4

Model 5

Model 6

nCt

0.0679

WC

WC

WC

WC

WC

nCconj

0.0631

0.04241

0.052

0.0444

0.3304

0.3606

nR = Cp

WC

0.0803

WC

WC

WC

WC

nRCO

− 0.5006

− 0.5641

− 0.491

− 0.48

− 0.7285

− 0.6265

nROR

− 0.34331

WC

− 0.2618

− 0.2579

− 0.503

− 0.5205

nArOH

WC

0.1229

0.1518

WC

0.6552

0.6582

nOH

WC

WC

WC

0.0187

WC

WC

Intercept

− 1.5373

− 1.644

− 1.6531

− 1.6723

− 2.80322

− 2.8386

  1. n, number of systems evaluated; Q2, the square of the coefficient of cross-validation; R2, the square of the correlation coefficient; s, standard deviation; F, Fisher statistic; WC, without contribution; nCt, number of total tertiary C (sp3); nCconj, number of non-aromatic conjugated C (sp2); nR = Cp, number of terminal primary C (sp2); nRCO, number of ketones (aliphatic); nROR, number of ethers; nArOH, number of phenolic groups; nOH, number of a hydroxyls