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Table 7 IC50 of the tested compounds against hepatocellular carcinoma cell line HePG2 and breast cancer cell line MCF-7

From: Design, synthesis and evaluation of anticancer activity of novel 2-thioxoimidazolidin-4-one derivatives bearing pyrazole, triazole and benzoxazole moieties

Compound no.

HepG-2 cell line

MCF-7 cell line

1

14.7

26.3

2

102

115

3

4.54

6.58

4

15.4

14.9

5

3.42

3.98

6

229

276

7

51.5

61.3

8

14.1

19.1

9

14.9

25.6

10

13.5

18.4

11a

243

249

11b

32.2

53.3

12

10.9

15.4

13

12.9

13.6

14

2.33

4.53

15

17.3

29

16

7.19

9.32

17

26.6

35.8

18

9.94

15.2

19

3.78

6.08

20

28.5

31.1

Doxorubicin

0.85

0.35