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Table 7 IC50 of the tested compounds against hepatocellular carcinoma cell line HePG2 and breast cancer cell line MCF-7

From: Design, synthesis and evaluation of anticancer activity of novel 2-thioxoimidazolidin-4-one derivatives bearing pyrazole, triazole and benzoxazole moieties

Compound no. HepG-2 cell line MCF-7 cell line
1 14.7 26.3
2 102 115
3 4.54 6.58
4 15.4 14.9
5 3.42 3.98
6 229 276
7 51.5 61.3
8 14.1 19.1
9 14.9 25.6
10 13.5 18.4
11a 243 249
11b 32.2 53.3
12 10.9 15.4
13 12.9 13.6
14 2.33 4.53
15 17.3 29
16 7.19 9.32
17 26.6 35.8
18 9.94 15.2
19 3.78 6.08
20 28.5 31.1
Doxorubicin 0.85 0.35