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Table 4 Cytotoxicity of compounds 1, 2, 3, 4, 5, 6, 7 and 8 against breast carcinoma cell line MCF-7

From: Design, synthesis and evaluation of anticancer activity of novel 2-thioxoimidazolidin-4-one derivatives bearing pyrazole, triazole and benzoxazole moieties

Concentration µg/mL Viability (%)/compound
1 2 3 4 5 6 7 8
500 7.18 22.34 3.86 9.26 4.23 37.15 16.27 8.07
250 13.95 34.51 9.62 20.84 9.06 51.49 29.38 16.56
125 24.82 45.28 14.87 28.63 15.38 74.01 38.69 24.56
62.5 32.93 73.69 20.65 36.59 21.75 88.63 49.16 31.88
31.25 45.06 86.13 26.83 42.67 28.91 97.89 71.32 40.31
15.6 60.83 94.56 36.54 48.54 36.42 100 86.04 52.76
7.8 79.62 98.94 45.02 65.18 42.37 100 93.76 68.49
3.9 85.21 100 60.89 80.95 50.16 100 98.51 82.53
2 92.37 100 78.15 91.79 65.24 100 100 91.42
1 98.64 100 86.41 95.48 76.35 100 100 97.17
0 100 100 100 100 100 100 100 100