Skip to main content

Advertisement

Table 1 Cytotoxicity of compounds 1, 2, 3, 4, 5, 6, 7 and 8 against hepatocellular carcinoma cell line HePG2

From: Design, synthesis and evaluation of anticancer activity of novel 2-thioxoimidazolidin-4-one derivatives bearing pyrazole, triazole and benzoxazole moieties

Concentration µg/mL Viability (%)/compound
1 2 3 4 5 6 7 8
500 5.26 19.86 2.97 7.48 3.04 31.67 12.58 6.31
250 10.68 28.74 7.28 14.53 6.31 46.23 20.64 14.96
125 18.97 39.45 11.49 21.84 10.25 68.92 31.75 20.85
62.5 25.14 68.17 16.85 29.41 16.43 83.64 42.31 26.43
31.25 34.72 79.52 23.72 38.63 22. 37 93.51 64.15 38.14
15.6 48.25 91.43 30.85 49.56 30.69 99.48 79.27 47.59
7.8 62.89 98.76 41.93 71.38 38.15 100 88.74 60.31
3.9 78.03 100 51.58 85.97 46.36 100 96.13 73.86
2 86.26 100 62.72 92.04 59.02 100 99.47 85.23
1 90.41 100 70.88 97.13 74.15 100 100 90.67
0 100 100 100 100 100 100 100 100