Table 53 Antiamoebic activity and toxicity profile of compound h16
From: Therapeutic potential of heterocyclic pyrimidine scaffolds
Compound | Antiamoebic activity | Toxicity profile | ||
|---|---|---|---|---|
(IC50 = µM) | SD (±) | (IC50 = µM) | Safety index | |
h16 | 0.10 | 0.014 | >Â 100 | >Â 1000 |
Metronidazole | 9 | 0.020 | >Â 100 | >Â 52.63 |