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Table 53 Antiamoebic activity and toxicity profile of compound h16

From: Therapeutic potential of heterocyclic pyrimidine scaffolds

Compound Antiamoebic activity Toxicity profile
(IC50 = µM) SD (±) (IC50 = µM) Safety index
h16 0.10 0.014 > 100 > 1000
Metronidazole 9 0.020 > 100 > 52.63
  1. SD standard deviation