Table 35 In vitro antimalarial activity results of active compounds
From: Therapeutic potential of heterocyclic pyrimidine scaffolds
Compounds | (%) Activity PfDHODH | IC50 against PfDHODH (µM) |
|---|---|---|
d7 | 67.474 ± 0.002 | 6 ± 1 |
d8 | 41 ± 3 | 4 ± 1 |
d9 | 77 ± 1 | – |
d10 | 60 ± 3 | 0.16 ± 0.01 |