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Table 35 In vitro antimalarial activity results of active compounds
From:
Therapeutic potential of heterocyclic pyrimidine scaffolds
Compounds
(%) Activity
Pf
DHODH
IC
50
against
Pf
DHODH (µM)
d7
67.474 ± 0.002
6 ± 1
d8
41 ± 3
4 ± 1
d9
77 ± 1
–
d10
60 ± 3
0.16 ± 0.01
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