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Table 35 In vitro antimalarial activity results of active compounds

From: Therapeutic potential of heterocyclic pyrimidine scaffolds

Compounds (%) Activity PfDHODH IC50 against PfDHODH (µM)
d7 67.474 ± 0.002 6 ± 1
d8 41 ± 3 4 ± 1
d9 77 ± 1
d10 60 ± 3 0.16 ± 0.01