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Table 31 Antiviral activity results (µM) of compounds c6 and c7

From: Therapeutic potential of heterocyclic pyrimidine scaffolds

Compounds Anti-HIV-1 activity in PBMCs HSV-1 plaque reduction assay
EC50 EC90 EC50 EC90
c6 2.7 19.8 6.3 16.4
c7 4.9 13.07 4.8 46.2
AZTa 0.016 0.20 > 10 > 10
Acyclovira > 100 > 100 0.11 0.69