Table 31 Antiviral activity results (µM) of compounds c6 and c7
From: Therapeutic potential of heterocyclic pyrimidine scaffolds
Compounds | Anti-HIV-1 activity in PBMCs | HSV-1 plaque reduction assay | ||
|---|---|---|---|---|
EC50 | EC90 | EC50 | EC90 | |
c6 | 2.7 | 19.8 | 6.3 | 16.4 |
c7 | 4.9 | 13.07 | 4.8 | 46.2 |
AZTa | 0.016 | 0.20 | >Â 10 | >Â 10 |
Acyclovira | >Â 100 | >Â 100 | 0.11 | 0.69 |