From: Therapeutic potential of heterocyclic pyrimidine scaffolds
Compound | Human cancer cell lines (IC50 = µM) | |||||
---|---|---|---|---|---|---|
A549 | Calu-3 | H460 | SK-BR3 | SGC-7901 | HT29 | |
b21 | 0.55 | 0.50 | 0.12 | 0.30 | 0.30 | 0.090 |
Adriamycin | 0.025 | – | – | – | – | 0.018 |
Docetaxel | – | 0.10 | 0.0097 | – | 0.0084 | – |
GW572016 | – | – | – | 0.017 | – | – |