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Table 23 In vitro anticancer activity of compound b21

From: Therapeutic potential of heterocyclic pyrimidine scaffolds

Compound

Human cancer cell lines (IC50 = µM)

A549

Calu-3

H460

SK-BR3

SGC-7901

HT29

b21

0.55

0.50

0.12

0.30

0.30

0.090

Adriamycin

0.025

0.018

Docetaxel

0.10

0.0097

0.0084

GW572016

0.017