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Table 23 In vitro anticancer activity of compound b21

From: Therapeutic potential of heterocyclic pyrimidine scaffolds

Compound Human cancer cell lines (IC50 = µM)
A549 Calu-3 H460 SK-BR3 SGC-7901 HT29
b21 0.55 0.50 0.12 0.30 0.30 0.090
Adriamycin 0.025 0.018
Docetaxel 0.10 0.0097 0.0084
GW572016 0.017