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Table 21 In vitro cytotoxicity of pyrido[2,3-d]pyrimidine derivatives against U937, THP-1 and Colo205 cancer cell lines

From: Therapeutic potential of heterocyclic pyrimidine scaffolds

Compounds IC50 (µg/ml)
U937 THP-1 Colo205
b17 8.16 ± 0.68 16.91 ± 1.42 19.25 ± 1.46
b18 6.20 ± 0.68 11.27 ± 1.67 15.01 ± 1.54
Etoposide (positive control) 17.94 ± 1.19 2.16 ± 0.15 7.24 ± 1.26