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Table 15 Anti-proliferative activity of b1 in human cancer cell lines

From: Therapeutic potential of heterocyclic pyrimidine scaffolds

Compound Human cancer cell lines
Origin Designation 48 h-MTT GI50 (µM) ± SD
b1 Colon carcinoma HCT-116 0.79 ± 0.08
Breast carcinoma MCF-7 0.64 ± 0.08
  MDA-MB468 1.51 ± 0.34
Lung carcinoma A549 2.01 ± 0.55
Ovarian carcinoma A2780 1.00 ± 0.11
Cervical carcinoma HeLa 0.90 ± 0.07
Pancreatic carcinoma Miacapa-2 1.25 ± 0.26