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Table 14 Antibacterial activity (zone of inhibition = mm) of most active compounds

From: Therapeutic potential of heterocyclic pyrimidine scaffolds

S. no

Pathogens

a29

a30

Bacitracin

Ciprofloxacin

1

Citrobacter sp.

37.16 ± 0.15

28.66 ± 0.15

0.00 ± 0.00

19.62 ± 0.18

2

Escherichia coli

36.66 ± 0.15

27.83 ± 0.20

0.00 ± 0.00

0.00 ± 0.00

3

Klebsiella sp.

32.50 ± 0.13

25.50 ± 0.27

0.00 ± 0.00

20.25 ± 0.16

4

Proteus mirabilis

28.66 ± 0.25

23.33 ± 0.17

0.00 ± 0.00

18.25 ± 0.16

5

Pseudomonas aeruginosa

30.66 ± 0.12

27.83 ± 0.27

0.00 ± 0.00

34.25 ± 0.16

6

S. parathyphi A

34.66 ± 0.12

24.50 ± 0.12

0.00 ± 0.00

27.75 ± 0.16

7

S. parathyphi B

32.50 ± 0.13

27.83 ± 0.20

0.00 ± 0.00

27.63 ± 0.18

8

Salmonella typhi

29.50 ± 0.25

19.66 ± 0.11

0.00 ± 0.00

20.25 ± 0.16

9

S. typhimurium

34.66 ± 0.12

23.33 ± 0.17

0.00 ± 0.00

18.75 ± 0.31

10

Shigella boydii

37.50 ± 0.07

28.66 ± 0.25

0.00 ± 0.00

17.75 ± 0.16

11

Shigella flexneri

35.66 ± 0.08

25.50 ± 0.27

0.00 ± 0.00

27.63 ± 0.18

12

Shigella sonnei

32.50 ± 0.13

37.50 ± 0.07

0.00 ± 0.00

21.75 ± 0.16

13

Staphylococcus aureus

37.50 ± 0.07

32.50 ± 0.13

26.75 ± 0.84

18.13 ± 0.48

14

Streptococcus faecalis

38.50 ± 0.12

35.66 ± 0.08

0.00 ± 0.00

0.00 ± 0.00