Table 10 Pharmacological evaluation (MIC = µg/ml) of the 2-substituted 5-(1,2-diarylethyl)-4,6-dichloropyrimidines
From: Therapeutic potential of heterocyclic pyrimidine scaffolds
| Â | a18 | a19 | a20 | a21 |
|---|---|---|---|---|
Axillary bacterial flora | ||||
 Staphylococcus xylosus | 20 | 100 | 100 | 100 |
 Staphylococcus epidermidis | 100 | 100 | 100 | 75 |
 Staphylococcus haemolyticus | 100 | 100 | 100 | 50 |
 Corynebacterium xerosis | 20 | 30 | 30 | 30 |
 Micrococcus luteus | 20 | 100 | 100 | 100 |
 Arcanobacterium haemolyticum | 10 | 10 | 10 | 10 |
Foot bacterial flora | ||||
 Staphylococcus epidermidis | > 100 | 100 | 100 | 75 |
 Staphylococcus hominis | 100 | 100 | 100 | 75 |
 Staphylococcus cohnii | 100 | 100 | 100 | 75 |
 Corynebacterium sp. g C | 100 | 100 | 100 | 75 |
 Corynebacterium sp. g B | 30 | 100 | 100 | 50 |
 Corynebacterium sp. g D2 | 30 | 100 | 50 | 50 |
 Micrococcus luteus | 20 | 100 | 100 | 75 |
 Micrococcus sedentarius | 30 | 100 | 100 | 75 |
 Acinetobacter sp. | > 1000 | > 500 | 50 | 30 |
 Moraxella sp. | 300 | 30 | 100 | 50 |
 Alcaligenes sp. | 1000 | > 500 | > 500 | > 500 |