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Fig. 4 | Chemistry Central Journal

Fig. 4

From: Anti-inflammatory effect of oligostilbenoids from Vitis heyneana in LPS-stimulated RAW 264.7 macrophages via suppressing the NF-κB activation

Fig. 4

Effect of 5 on COX-2 and iNOS expression in dose-dependent manner (1–30 µM). Raw264.7 cells were treated with 5 μg/mL LPS for 18 h with or without VH07 and then harvested and lysated to immunoblottings with COX-2, iNOS and β-actin antibodies. b Effect of 5 on LPS-induced COX-2 was analyzed by qPCR (***significant as compared to control, *p < 0.05; #significant as compared to LPS group, n = 5). c Effect of 5 on PGE2 production. RAW 264.7 cells were incubated with 5 μg/mL LPS for 18 h with or without 5 and amounts of PGE2 in medium was determined using PGE2-specific ELISA assays. (***significant as compared to control, *p < 0.05; #significant as compared to LPS group, n = 4)

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