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Table 3 Results of freezing–thawing and short term stability study

From: Determination of flutamide and two major metabolites using HPLC–DAD and HPTLC methods

 

Spiked human plasma

Spiked urine

Flutamide

Flu-1

Flu-3

Flutamide

Flu-1

Flu-3

Freezing thaw cycle

 HPTLC method

  SDa

3.143

1.725

2.901

2.524

1.301

3.083

 HPLC method

  SDa

2.028

1.75

1.730

2.21

2.402

1.980

Short term stability

 HPTLC method

  SDa

2.44

2.86

3.18

2.60

3.01

3.08

 HPLC method

  SDa

2.00

1.54

3.04

2.43

2.64

3.52

  1. aAverage of 3 determinations