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Table 8 Evaluation of hypoglycemic activity: effect of compound on % decrease in blood glucose in diabetic mice

From: Biological potential of thiazolidinedione derivatives of synthetic origin

Compounds

0 h

2 h

4 h

6 h

24 h

Control

252.53 ± 4.254

4.74 ± 0.68

7.9 ± 4.32

13.43 ± 2.68

3.18 ± 4.35

Piogiltazone

250.75 ± 5.21

31.07 ± 6.74

37.48 ± 5.37

45.41 ± 3.67

10.3 ± 6.53

18

252.79 ± 2.85

29.34 ± 4.53

36.52 ± 5.43

46.64 ± 4.52

6.70 ± 6.51

19

252.19 ± 4.35

24.7 ± 3.97

34.76 ± 6.51

37.89 ± 5.43

5.19 ± 7.74

20

254.38 ± 4.53

26.64 ± 5.28

34.26 ± 5.67

37.05 ± 4.62

4.19 ± 5.43

21

253.60 ± 5.64

22.9 ± 4.72

35.6 ± 5.53

40.41 ± 5.97

3.87 ± 6.53

22

252.73 ± 5.23

29.01 ± 6.54

36.47 ± 4.65

39.21 ± 5.74

3.0 ± 3.75