Table 6 Hypoglycemic effect of synthesized compounds
From: Biological potential of thiazolidinedione derivatives of synthetic origin
Compounds | Blood glucose level mg/dl (mean ± SE) | |||
|---|---|---|---|---|
0Â h | 3Â h | 6Â h | 24Â h | |
11 | 376.4 ± 21.00 | 342.8 ± 21.58 | 315.2 ± 21.66 | 276 ± 21.79 |
12 | 326.2 ± 25.32 | 300 ± 25.03 | 278.2 ± 25.76 | 245.2 ± 25.91 |
13 | 355 ± 24.59 | 322.8 ± 24.10 | 253.8 ± 23.45 | 231.4 ± 23.48 |
Pioglitazone | 402.2 ± 28.7 | 363.4 ± 26.08 | 302.4 ± 26.87 | 232.2 ± 20.53 |
Metformin | 441.8 ± 18.71 | 399.4 ± 17.72 | 289.4 ± 18.46 | 219.6 ± 18.40 |
Vehicle control | 304.2 ± 36.81 | 308.2 ± 36.85 | 309 ± 37.92 | 310.4 ± 39.57 |
Diabetic control | 322.2 ± 22.96 | 337 ± 23.59 | 347 ± 24.01 | 363.4 ± 24.0 |
Normal control | 120.33 ± 7.76 | 125.66 ± 2.08 | 126.66 ± 3.05 | 129.33 ± 1.52 |