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Table 26 Cytotoxicity of synthesized thiazolidinediones

From: Biological potential of thiazolidinedione derivatives of synthetic origin

Compounds

IC50 (μg/ml)

HepG2

HC-60

KB

LLC

LNCaP

LU-1

MCF-7

SW-480

80

> 100

82.2 ± 4.5

44.1 ± 3.6

87.4 ± 6.3

77.4 ± 5.8

52.9 ± 3.4

66.0 ± 2.7

71.4 ± 3.6

81

86.3 ± 6.4

75.3 ± 3.9

84.6 ± 4.2

> 100

81.6 ± 6.3

> 100

32.8 ± 1.4

90.1 ± 4.8

82

78.4 ± 5.8

92.3 ± 5.3

74.1 ± 5.1

90.1 ± 7.7

84.2 ± 4.1

65.5 ± 4.1

52.7 ± 3.6

85.4 ± 7.4

Ellipticine

1.45 ± 0.08

0.56 ± 0.04

0.43 ± 0.05

0.98 ± 0.04

0.86 ± 0.06

1.29 ± 0.11

0.49 ± 0.04

0.64 ± 0.05