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Table 1 Chemical structure, yield and melting point of the synthesized compounds

From: Synthesis, anti-angiogenic and DNA cleavage studies of novel N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)piperidine-4-carboxamide derivatives

Compound

R1/R2/R3

Yield (%)

MP (°C)

10a

84

124

10b

81

135

10c

83

134

10d

85

145

10e

88

154

10f

86

153

12a

86

100

12b

85

88

12c

82

158

14a

86

143

14b

81

135

14c

82

136