Table 3 Stability tests of lesinurad in rat plasma under different storage conditions (n = 6)
From: Determination of lesinurad in rat plasma by a UHPLC–MS/MS assay
Concentration (ng/mL) | Room temperature | 4 °C | Freeze–thaw (3 cycles) | − 20 °C (30 days) | ||||
|---|---|---|---|---|---|---|---|---|
RSD % | RE % | RSD % | RE % | RSD % | RE % | RSD % | RE % | |
100 | 6.48 | − 2.54 | 8.25 | − 6.02 | 9.22 | 0.39 | 1.83 | 0.32 |
1000 | 4.82 | − 6.62 | 6.83 | − 5.70 | 7.82 | − 10.16 | 6.71 | − 8.77 |
25,000 | 3.41 | − 4.54 | 2.06 | 1.93 | 8.19 | 6.48 | 7.38 | 8.45 |