Table 2 EC50 values of target compounds against Xoo and Rs
From: Synthesis and biological activity of myricetin derivatives containing 1,3,4-thiadiazole scaffold
Compd. | Xoo | Rs | ||||
|---|---|---|---|---|---|---|
Regression equation | r | EC50 (µg/mL) | Regression equation | r | EC50 (µg/mL) | |
2 | y = 2.513x + 0.902 | 0.99 | 42.7 ± 2.6 | / | / | / |
3a | y = 2.885x + 0.454 | 0.99 | 38.6 ± 1.4 | / | / | / |
3b | y = 1.199x + 3.420 | 0.99 | 20.8 ± 3.6 | y = 2.685x + 0.762 | 0.99 | 37.9 ± 1.0 |
3d | y = 2.328x + 2.418 | 0.97 | 12.9 ± 5.8 | y = 2.770x-0.154 | 0.99 | 72.6 ± 1.6 |
3e | / | / | / | y = 2.485x + 0.925 | 0.98 | 43.6 ± 3.8 |
3f | y = 1.982x + 2.314 | 0.98 | 22.7 ± 3.6 | y = 3.004x-0.332 | 0.99 | 59.6 ± 2.0 |
3i | y = 1.401x + 2.989 | 0.99 | 27.3 ± 1.8 | y = 2.365x + 0.786 | 0.99 | 60.6 ± 2.1 |
3m | y = 2.723x + 1.565 | 0.98 | 18.3 ± 3.6 | / | / | / |
3p | y = 2.058x + 1.979 | 0.99 | 29.4 ± 1.0 | / | / | / |
3o | / | / | / | y = 1.017x + 3.375 | 0.96 | 39.6 ± 5.3 |
Thiadiazole-copper a | y = 1.999x + 1.047 | 0.99 | 94.9 ± 2.2 | y = 0.930x + 3.028 | 0.98 | 131.7 ± 2.9 |