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Table 1 The experimental data obtained for the three responses based on the CCD matrix

From: Optimization of phenolics and flavonoids extraction conditions of Curcuma Zedoaria leaves using response surface methodology

Run no Type Temperature (X 1 ) Time (X 2 ) Solvent ratio (X 3 ) Phenolic
content mg/g GAE
Flavonoid content
mg QE/g extract
1 Fact 80.0 80.0 90.0 131.96 6.18
2 Fact 60.0 120.0 70.0 116.76 6.00
3 Center 70.0 100.0 80.0 122.20 6.24
4 Fact 80.0 120.0 70.0 122.90 6.07
5 Axial 53.18 100.0 80.0 116.14 6.09
6 Center 70.0 100.0 80.0 122.64 6.23
7 Axial 70.0 66.36 80.0 115.32 6.31
8 Axial 86.82 100.0 80.0 135.77 6.05
9 Axial 70.0 100.0 96.82 119.17 6.35
10 Fact 80.0 80.0 70.0 121.80 6.21
11 Axial 70.0 100.0 63.18 105.10 6.06
12 Fact 80.0 120.0 90.0 122.43 6.22
13 Fact 60.0 80.0 70.0 98.76 6.08
14 Fact 60.0 80.0 90.0 115.83 6.33
15 Center 70.0 100.0 80.0 122.32 6.23
16 Center 70.0 100.0 80.0 122.24 6.21
17 Fact 60.0 120.0 90.0 122.30 6.38
18 Axial 70.0 133.64 80.0 122.27 6.26
19 Center 70.0 100.0 80.0 122.55 6.22
20 Center 70.0 100.0 80.0 122.25 6.23