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Fig. 4 | Chemistry Central Journal

Fig. 4

From: Synthesis, crystallographic characterization, molecular docking and biological activity of isoquinoline derivatives

Fig. 4

a Changes in body weight of CFA-induced RA in rat with compounds 9 and 15. b Effect of test compounds (50 mg/kg) on CFA-induced arthritis in rats with compounds 9 and 15. c Effect on hotplate time response with compounds 9 and 15. d Effect on spontaneous motor activity in CFA rats with compounds 9 and 15. Data represent the mean ± SEM (n = 6 for each group); *significance versus control (P ≤ 0.05); asignificance versus CFA group (P ≤ 0.05)

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