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Table 3 Suzuki coupling of aryl bromides 5b–g with phenylboronic acid using the catalyst 4 under thermal  and microwave conditions

From: Novel pyridine-based Pd(II)-complex for efficient Suzuki coupling of aryl halides under microwaves irradiation in water

Entry

R

Conversion

∆ yield %

MW yield %

1

H

100

78

92

2

2-COCH3

100

61

93

3

4-OCH3

100

70

90

4

4-COOH

100

74

89

5

4-CH3

100

24

60

6

4-OH

100

77

87

  1. Conditions: Bromide: 1 mmol; phenylboronic acid: 1.2 mmol; TBAB: 0.6 mmol; KOH: 2 mmol; water: 5 mL, Pd-complex 4: 0.25 mol%, microwave heating (300 W) at 110 °C for 10 min and thermal heating at 100 °C for 3 h
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BMC Chemistry

ISSN: 2661-801X

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