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Table 2 Antifungal activity of synthesized compound (zone of inhibition in diameter in mm)

From: Antimicrobial activity of thiophene derivatives derived from ethyl (E)-5-(3-(dimethylamino)acryloyl)-4-methyl-2-(phenylamino)thiophene-3-carboxylate

Tested microorganisms comp. no

Fungi

Inhibition zone diameter in mm and (%) value

Aspergillus fumigates

Syncephalastrum racemosum

Geotricum candidum

Candida albicans

St.

Amphotericin B

23.7 ± 0.1

19.7 ± 0.2

28.7 ± 0.2

25.4 ± 0.1

2

15.7 ± 0.33 (66.2%)

13.8 ± 0.25 (70.1%)

18.3 ± 0.34 (64.8%)

15.2 ± 0.53 (59.8%)

3

18.7 ± 0.36 (78.9%)

16.9 ± 0.27 (85.8%)

13.4 ± 0.65 (46.7%)

10.9 ± 0.23 (42.9%)

4

16.3 ± 0.53 (68.8%)

13.4 ± 0.49 (68.0%)

15.9 ± 0.71 (55.4%)

17.3 ± 0.62 (68.1%)

5

15.9 ± 0.62 (67.1%)

18.9 ± 0.58 (95.9%)

19.1 ± 0.54 (66.6%)

15.8 ± 0.38 (62.2%)

6

18.2 ± 0.57 (76.8%)

17.4 ± 0.6 (88.3%)

17.8 ± 0.72 (62.0%)

12.9 ± 0.37 (50.8%)

7a

12.3 ± 0.39 (51.9%)

17.2 ± 0.16 (87.3%)

24.6 ± 0.58 (85.7%)

12.7 ± 0.38 (50.0%)

7b

23.7 ± 0.1 (100%)

19.7 ± 0.2 (100%)

28.7 ± 0.2 (100%)

25.4 ± 0.1 (100%)

8

23.7 ± 0.1 (100%)

19.7 ± 0.2 (100%)

28.7 ± 0.2 (100%)

25.4 ± 0.1 (100%)

9

14.9 ± 0.61 (62.9%)

13.7 ± 0.42 (69.5%)

15.9 ± 0.38 (55.4%)

14.7 ± 0.52 (57.9%)

10

17.3 ± 0.49 (73.0%)

13.3 ± 0.39 (67.5%)

14.6 ± 0.52 (50.9%)

15.1 ± 0.48 (59.4%)

11a

13.6 ± 0.25 (57.4%)

11.7 ± 0.34 (59.4%)

16.5 ± 0.58 (57.5%)

13.4 ± 0.45 (52.8%)