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Table 3 Inhibition activities of 7, 1315, and sunitinib against in vitro tube formation

From: Structural optimization and evaluation of novel 2-pyrrolidone-fused (2-oxoindolin-3-ylidene)methylpyrrole derivatives as potential VEGFR-2/PDGFRβ inhibitors

Compound R IC50 (μM)
Area
Sunitinib 1.54 ± 0.08
7 –SO2N(CH2CH2Cl)2 0.76 ± 0.11
13 –OMe 0.74 ± 0.16
14 –OH 0.62 ± 0.07
15 –SH 0.53 ± 0.11
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